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CVP (chemotherapy) : ウィキペディア英語版 | CHOP
CHOP is the acronym for a chemotherapy regimen used in the treatment of non-Hodgkin lymphoma. CHOP consists of: * (C)yclophosphamide, an alkylating agent which damages DNA by binding to it and causing the formation of cross-links * (H)ydroxydaunorubicin (also called doxorubicin or Adriamycin), an intercalating agent which damages DNA by inserting itself between DNA bases * (O)ncovin (vincristine), which prevents cells from duplicating by binding to the protein tubulin * (P)rednisone or (P)rednisolone, which are corticosteroids. == Dosing regimen ==
R-Maxi-CHOP is used in mantle cell lymphoma and is given in 21-day intervals, alternating with R-HDAC (rituximab + high-dose cytarabine).〔(Nordic Protocol (Maxi-CHOP and High Dose Cytarabine) for Mantle Cell Lymphoma (MCL) )〕 In most other non-Hodgkin lymphomas (excluding some aggressive forms), standard-dose ()-CHOP is generally used as first-line therapy.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「CHOP」の詳細全文を読む
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